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目的了解佛冈地区的结直肠癌(CRC)患病情况并探讨其影响因素。方法在佛冈县随机抽选48个村或社区作为调查点。先统一发放调查问卷以确定高危人群,然后以粪便隐血试验作为初筛。初筛阳性者以结肠镜检作为复筛以确诊,并采用logistic回归分析影响CRC发生的因素。结果筛查目标为47 400人,回收有效问卷34 286份,顺应率为72.33%;接受初筛26 572人,阳性1 662人,阳性率6.25%;接受结肠镜检980例,发现结直肠癌35例(3.57%);高亚硝酸盐(OR=2.073)、高脂饮食(OR=2.462)和胆囊结石(OR=2.659)为CRC的危险因素,高膳食纤维(OR=0.637)为保护因素。结论结直肠癌筛查能够有效地从无症状人群中找到结直肠癌患者,利于早期治疗,提高预后。佛冈地区居民的CRC筛查依从性较低,应注意加强健康教育。
Objective To investigate the prevalence of colorectal cancer (CRC) in Fogang area and to explore its influencing factors. Methods A total of 48 villages or communities were randomly selected in Fogang County as investigation points. First unified questionnaires to determine the distribution of high-risk groups, and then fecal occult blood test as a preliminary screening. Primary screening positive colonoscopy as screened to confirm the diagnosis and use of logistic regression analysis of factors that affect CRC. RESULTS: The screening target was 47 400, effective questionnaires were recalled 34 286, the compliance rate was 72.33%; 26 572 were initially screening, 1 662 were positive, the positive rate was 6.25%; Colonoscopy was performed in 980 cases and colorectal cancer was found 35 cases (3.57%) had high risk of CRC, high-nitrite (OR = 2.073), high fat diet (OR = 2.462) and gallstone (OR = 2.659) . Conclusion Colorectal cancer screening can effectively find patients with colorectal cancer from asymptomatic population, which will benefit early treatment and improve prognosis. Residents in Fogang Prefecture have a low compliance with CRC screening and should pay attention to strengthening health education.