本文报道1例病变累及颅底和眼眶的晚期筛窦癌接受颅面联合切除术,并对此手术的适应症、进颅方式、颅底缺损修补及并发症进行了讨论。作者认为颅面联合切除术能在直视下彻底切除侵及颅底(包括硬脑膜)的肿瘤,只要耳鼻咽喉科和神经外科密切配合,手术安全可靠,可作为晚期筛窦癌的外科治疗选择。 This article reports a case of advanced ethmoid carcinoma involving the skull base and orbital sinus cancer underwent craniofacial resection, and the indications for this operation, cranial approach, skull base defect repair and complications were discussed. The author believes that craniofacial resection can be completely under direct vision to invade the skull base (including dura mater) tumors, as long as the close cooperation of otorhinolaryngology and neurosurgery, surgical safety and reliability, can be used as a surgical treatment of advanced ethmoid sinus cancer .