论文部分内容阅读
对20例鼻咽癌患者及12例正常人外周血培养细胞染色体的观察表明,患者自发畸变率、丝裂霉素C及平阳霉素诱发畸变率明显高于正常对照(P<0.001);患者的自发和丝裂霉素C诱发微核形成率也高于正常人(P<0.001)。本实验结果为鼻咽癌患者存在体细胞染色体不稳定性提供了实验证据。
Chromosome observation of peripheral blood cells from 20 patients with nasopharyngeal carcinoma and 12 normal controls showed that patients with spontaneous aberration, mitomycin C and pingyangmycin induced distortion rate was significantly higher than the normal control (P <0.001); patients The spontaneous and mitomycin C-induced micronucleus formation rates were also higher than those in normal subjects (P <0.001). The experimental results for the existence of somatic cell chromosome instability in patients with nasopharyngeal carcinoma provide experimental evidence.