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以人肺巨细胞癌细胞系ＰＬＡ－８０１的两个细胞克隆Ｃ株及Ｄ株，建立了ＰＬＡ－８０１Ｃ及ＰＬＡ－８０１Ｄ裸鼠皮下移植瘤模型，以人肺腺癌裸鼠移植瘤培养细胞Ａｎｉｐ９７３，复制了Ａｎｉｐ９７３裸鼠皮下移植瘤及腹水瘤模型，对其生物学特性进行了研究。这４株移植瘤模型的淋巴结及肺转移率由低到高依次为ＰＬＡ－８０１Ｃ皮下瘤（０％，０％）、Ａｎｉｐ９７３皮下瘤（８．６％，４．３％）、Ａｎｉｐ９７３腹水瘤（１００％，１２．０％）、ＰＬＡ－８０１Ｄ皮下瘤（１００％，３１．６％）。具有同源性的不同转移力人肺癌裸鼠移植模型的建立对肺癌转移机理的对比研究具有意义
The human lung giant cell carcinoma cell line PLA-801 cell clones C and D strains were established PLA-801C and PLA-801D subcutaneous xenograft model of nude mice with human lung adenocarcinoma xenografts cultured cells Anip973 , Replicate Anip973 xenograft tumor and ascites tumor model in nude mice and study its biological characteristics. The rates of lymph node and lung metastases in the four xenograft models from low to high were PLA-801C subcutaneous tumor (0%, 0%), Anip973 subcutaneous tumor (8.6%, 4.3%), Anip973 ascites tumor 100%, 12.0%), PLA-801D subcutaneous tumor (100%, 31.6%). Establishment of a Nude Mouse Model of Homologous Lung Metastasis with Different Metastatic Ability The comparative study on the metastatic mechanism of lung cancer is of great significance