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目的：探讨心外科重症监护室（CSICU）患者急性生理学及慢性健康状况评分系统Ⅱ（APACHEⅡ）与血小板计数水平的相关性及对患者预后的评估价值。方法选择2013年12月至2014年11月沈阳军区总医院CSICU收治的2340例患者，检测其血小板计数水平，所有患者在入ICU 24 h内进行APACHEⅡ评分，评分以各项指标最差值计算，并按APACHEⅡ评分分为组Ⅰ（34分），根据患者预后分为存活组和死亡组，根据血小板计数水平分为血小板正常组与血小板减少组，分析血小板计数与APACHEⅡ评分的关系。结果 APACHEⅡ评分组Ⅰ与组Ⅱ间血小板计数无明显差异，组Ⅱ血小板计数结果明显高于组Ⅲ，组Ⅲ血小板计数结果明显高于组Ⅳ。死亡组患者血小板计数结果明显高于存活组，差异有统计学意义（P<0.05）；死亡组APACHEⅡ得分（24.30±7.95）分，生存组得分（7.68±3.91）分，差异有统计学意义（P<0.001）。APACHEⅡ评分与血小板计数呈显著负相关（r=-0.729，P<0.001）。结论 CSICU患者血小板计数与APACHEⅡ评分存在相关性，对判断病情及预后具有重要意义。“,”ObjectiveTo explore the relationship between acute physiology and chronic health evaluation Ⅱ (APACHEⅡ) score and platelet count and the prognosis of patients admitted to Cardiac Surgery Intensive Care Unit within 24 hours.Methods The platelet counts were measured in 2340 cases, all patients were scored by the worst index level in the APACHEⅡ score system within 24 hour after admission,The patients were divided into 4 groups: groupⅠ(34 score) according to APACHEⅡ scores.All the patients were divided into two groups based on their prognosis:survival group and death group.According to the level of platelet count, all the patients were divided into normal group and thrombocytopeniua group. The relationships between APACHEⅡ score and platelet count and prognosis were analyzed.Results The platelet count was the lowest in group Ⅳ,than in group Ⅲ、group II and groupⅠ(P<0.05). The platelet count in the survival group was significantly higher than the dead group (P<0.05). The APACHEⅡscore in the survival group was (7.68±3.91) scores,which was significantly lower than 24.30±7.95 scores in the dead group(P<0.001). The level of platelet count was negatively related to APACHEⅡ score (r=-0.729,P<0.001).Conclusions The level of platelet count was negatively related to APACHEⅡ score, can be used to evaluate the severity and prognosis of patients of cardiac surgery ICU.