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角化过度性手足癣９０例，随机分为Ａ、Ｂ、Ｃ３组，Ａ组采用斑蝥洗剂加醋浸泡后交替外用达克宁霜、华佗膏、１％克霉唑霜，并塑料膜封包；Ｂ组单纯用斑蝥洗剂加醋浸泡后封包；Ｃ组交替外用达克宁、华佗膏、１‰克霉唑霜加封包。４周后进行疗效判断，其结果Ａ组疗效优于Ｂ、Ｃ二组，Ｐ＜０．０５。说明斑蝥洗剂具有抑制真菌，角质剥脱作用，与外用药膏联用，取长补短增强疗效可提高治愈率
90 cases of hyperkeratotic hand, foot and ringworm were randomly divided into A, B and C3 groups. Group A was treated with cantharidin lotion and vinegar after soaking and then topical floxuron cream, Hua Tuo cream and 1% clotrimazole cream and plastic film package. Group B was treated with cantharidin lotion and vinegar soak, and then packed. Group C was given alternated topical bleaching cream, Hua Tuo cream and 1 ‰ clotrimazole cream. Four weeks later, the curative effect was evaluated. The results showed that the efficacy of group A was better than that of group B and C (P <0.05). Explain that the mackerel lotion has the function of inhibiting the fungus and the keratosis exfoliation, and the combination of topical and ointment, and enhances the curative effect to improve the cure rate