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1例38岁女性患者,因服用酮康唑导致药物性肝损害入院。入院后给予复方甘草酸苷注射液100ml(含甘草酸苷200mg)加入5%葡萄糖注射液250ml静脉滴注,共2周。随后,患者出现全身水肿,双下肢明显,血压波动在136～140/90～100mmHg,血钾2.56mmol/L。停用该药,给予螺内酯片及氯化钾控释片治疗,7d后症状好转。入院26d痊愈出院,随访2周无不适。
A 38-year-old female patient admitted to hospital with medical-induced liver injury due to ketoconazole. After admission compound glycyrrhizin injection 100ml (containing glycyrrhizin 200mg) added 5% glucose injection 250ml intravenous infusion for 2 weeks. Subsequently, patients with systemic edema, both lower extremities obvious, blood pressure fluctuations in the 136 ~ 140/90 ~ 100mmHg, potassium 2.56mmol / L. The drug was discontinued, spironolactone tablets and potassium chloride controlled release tablets were given, and the symptoms improved after 7 days. Admitted to hospital 26d discharged, 2 weeks follow-up without discomfort.