颅内出血是早产儿常见的严重疾患,病死率高,存活者也常有神经系统后遗症。早产儿颅内出血主要表现为室管膜下出血(SEH)及脑室内出血(IVH),胎龄越小,发病率越高,国内报告早产儿缺氧性颅内出血的发病率为40%～50%,病死率达50%,因此预防早产儿颅内出血显得尤为重 Intracranial hemorrhage is a common serious illness in preterm children, high mortality, survivors often have nervous system sequelae. Preterm infants with intracranial hemorrhage mainly manifested as subependymal hemorrhage (SEH) and intraventricular hemorrhage (IVH), the smaller the gestational age, the higher the incidence, the incidence of hypoxic intracranial hemorrhage in preterm infants reported 40% to 50% , Fatality rate of 50%, so to prevent intracranial hemorrhage in preterm children is particularly important