自然杀伤(NK)细胞是肿瘤鉴视中的重要细胞。作者用~(51)Cr标记K562细胞观察末稍血中NK细胞的活性,同时用单克隆抗体检测血中淋巴细胞亚群。正常人38例NK活性为49.7±2.2%,肝硬化57例为35.6±1.8%,有明显下降(P<0.001);肝硬化合并肝癌22例为27.6±3.5%,也有明显下降(P<0.001)。肝硬化合并肝癌组比肝硬化组也低(P<0.05)。作者以单克隆抗体检测 Natural killer (NK) cells are important cells in tumor identification. The authors used K51 cells labeled with (51)Cr to observe the activity of NK cells in the peripheral blood and to detect lymphocyte subsets in the blood with monoclonal antibodies. The normal NK activity was 49.7±2.2% in 38 cases, 35.6±1.8% in 57 cirrhosis cases (P<0.001), and 27.6±3.5% in liver cirrhosis with liver cancer in 22 cases (P<0.001). ). Liver cirrhosis patients with liver cancer were also lower than those with liver cirrhosis (P<0.05). The authors tested with monoclonal antibodies