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目的:应用实时三维超声心动图(RT-3DE)评价无症状饮酒者随着饮酒时间因素改变对左心房功能的影响。方法:选取30例体检健康不饮酒男性作为对照(A组);61例无临床症状男性饮酒者根据饮酒时间长短分为2组:30例饮酒时间5~9年者为B组,31例饮酒时间10~20年者为C组。对3组行常规超声及RT-3DE检查。常规测量参数包括左室舒张末期内径(LVDd)、舒张末期室间隔厚度(IVSTd)、左室射血分数(LVEF)及短轴缩短率(FS)。RT-3DE测量参数包括左心房最大容积(LAVmax)、最小容积(LAVmin)、左心房主动收缩前容积(LAVp)、左心房被动射血分数(LAPEF)、左心房主动射血分数(LAAEF)、左心房整体射血分数(LATEF)。结果:B组所有指标与A组比较无统计学意义(均P>0.05)。C组LAVmin、LAVmax、LAVp、LAAEF、LATEF与A、B组比较明显增大(均P<0.05),LAPEF明显减少(均P<0.05)。结论:RT-3DE可以有效评价无症状饮酒者随着饮酒时间因素改变左心房功能的变化情况。
Objective: To evaluate the effect of change of drinking time factors on left atrial function in asymptomatic drinkers by real-time three-dimensional echocardiography (RT-3DE). Methods: 30 healthy non-drinking men were selected as the control group (A group); 61 non-clinical symptoms of male drinkers were divided into two groups according to the length of drinking: 30 cases of drinking time of 5 to 9 years were in group B, 31 cases of drinking 10 to 20 years for the C group. Three groups of routine ultrasound and RT-3DE examination. Routine measurement parameters include left ventricular end-diastolic diameter (LVDd), end-diastolic ventricular septal thickness (IVSTd), left ventricular ejection fraction (LVEF) and short axis shortening (FS). RT-3DE measurements included LAVmax, LAVmin, LAVp, LAPEF, LAAEF, and left ventricular ejection fraction. Left atrial total ejection fraction (LATEF). Results: All indexes in group B were not statistically significant compared with group A (all P> 0.05). The LAVmin, LAVmax, LAVp, LAAEF and LATEF in group C were significantly increased compared with those in group A and B (both P <0.05) and LAPEF were significantly decreased (all P <0.05). Conclusion: RT-3DE can effectively evaluate the change of left atrial function in asymptomatic drinkers with drinking time.