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目的:分析对乙型肝炎病毒(HBV)携带孕妇分娩新生儿实施母婴阻断的方法和效果。方法:对2002年7月~2004年6月长兴地区4 446例孕妇筛查HBV标志物,对HBsAg阳性孕妇实行乙肝免疫球蛋白(HB IG)注射宫内阻断加婴儿HB IG和乙肝疫苗注射主、被动联合免疫。结果:对本地区乙肝病毒母婴传播阻断效果确切,有效率达96.8%。结论:宫内阻断结合婴儿联合免疫是阻断HBV母婴传播的有效方法。
Objective: To analyze the method and effect of maternal-neonatal block in newborn infants born to hepatitis B virus (HBV) pregnant women. Methods: 4 446 pregnant women in Changxing district from July 2002 to June 2004 were screened for HBV markers, HBsAg-positive pregnant women were given HBIG injection intrauterine ablation plus HBIG and hepatitis B vaccine Lord, passive combined immunization. Results: The effect of blocking the mother-to-child transmission of hepatitis B virus in this area was exact and the effective rate was 96.8%. Conclusion: Intrauterine block combined with infant co-immunization is an effective way to block the transmission of HBV from mother to infant.