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目的讨论分析CPAP正压通气治疗新生儿呼吸窘迫综合征的疗效。方法将60例新生儿呼吸窘迫综合征的患儿随机分为两组:治疗组与对照组,每组患儿有30例,治疗组应用CPAP正压通气治疗,设置参数:氧流量为6-8 L/min,吸入氧浓度(Fi O_2)0.3-0.6,压力为4-8 cm H_2O(1 cm H2O=0.098 k Pa)。对照组应用头罩吸氧方式进行治疗(氧流量为4-6 L/min)。若患儿经过治疗没有效果则改用气管插管、机械通气的方式进行治疗。对两组患儿的治疗效果进行比较观察。结果治疗组27例治愈,2例改变治疗方式应用气管插管进行治疗,1例患者自动出院,治愈率为90%;对照组18例患儿治愈,8例患儿改变治疗方法应用气管插管方法治疗,4例死亡,治愈率为60%。两组患儿的治疗效果对比,有显著的统计学差异(P<0.05)。结论 CPAP正压通气治疗新生儿呼吸窘迫综合征的临床效果良好,值得推广应用。
Objective To discuss the effect of CPAP positive pressure ventilation on neonatal respiratory distress syndrome. Methods Sixty neonates with respiratory distress syndrome were randomly divided into two groups: the treatment group and the control group, with 30 cases in each group. The treatment group was treated with CPAP positive pressure ventilation and the parameters of oxygen flow were 6- 8 L / min, FiO 2 0.3-0.6 and pressure 4-8 cm H 2 O (1 cm H 2 O = 0.098 kPa). The control group was treated with hood oxygen therapy (oxygen flow of 4-6 L / min). If the child has no effect after treatment is replaced by endotracheal intubation, mechanical ventilation for treatment. The treatment effect of two groups of children were compared. Results In the treatment group, 27 cases were cured and 2 cases were treated by endotracheal intubation. One patient was discharged automatically and the cure rate was 90%. In the control group, 18 cases were cured and 8 cases were treated by tracheal intubation Methods of treatment, 4 patients died, the cure rate was 60%. There was significant difference between the two groups in the treatment effect (P <0.05). Conclusion CPAP positive pressure ventilation in the treatment of neonatal respiratory distress syndrome has a good clinical effect and is worth popularizing and applying.