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本文调查发现，ＥＰＥＣ相关血清型的大肠杆菌在不同年龄组腹泻患者中检出率未见明显差异，且在相同年龄段的腹泻患者和正常人之间，检出率也未见明显差异，表明用鉴定血清型来进行ＥＰＥＣ的诊断或流行病学调查可能不能正确反映该菌感染的真实状况。本次调查分离的ＥＰＥＣ相关血清型的大肠杆菌菌株进行了ｅａｅＡ基因的检测。检出３株阳性菌株，均分离自１岁以内的腹泻婴儿，而分离自年龄大于１周岁的腹泻患者及正常人的ＥＰＥＣ相关血清型大肠杆菌，ｅａｅＡ基因均为阴性。结果提示： ｅａｅＡ基因是鉴定ＥＰＥＣ的标示物之一，应用于流行病学调查有良好的前景；该市腹泻婴幼儿中有ｅａｅＡ基因阳性的ＥＰＥＣ的流行，可能是该市婴幼儿腹泻的重要病原菌之一。
This investigation found that EPEC-associated serotypes of Escherichia coli in patients of different age groups had no significant difference in the detection rate of diarrhea, and in the same age group of diarrhea patients and normal people, the detection rate also showed no significant difference, indicating The diagnosis or epidemiological investigation of an EPEC using an identified serotype may not accurately reflect the true status of the infection. The eaeA gene was tested in the E. coli isolates from the EPEC-associated serotypes of this survey. Three positive strains were detected and all were isolated from infants with diarrhea within 1 year of age. However, the eaeA gene was negative for EPEC-associated serotypes of Escherichia coli isolated from diarrhea patients older than 1 year old and normal controls. The results suggest that the eaeA gene is one of the markers for the identification of EPEC and has a good prospect for epidemiological investigation. The prevalence of eaeA gene-positive EPEC in diarrhea infants and young children in this city may be an important pathogen of infantile diarrhea in this city one.