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对排除了引起血清免疫球旦白水平改变的常见疾病之原发性高血压患者54例作 IgG、IgA 和 IgM 测定,并与血压正常组51例对照。表明:患者 IgG 明显增高(P<0.01),伴有心脏损害者 IgG 和 IgA 均显著增高(P<0.01)。结合文献讨论了高血压者免疫功能改变的机理及其与并发症和治疗用药的关系。提示:对患者测定 Ig 水平有一定临床意义,IgA 过高应考虑并发心脏损害的可能。
Fifty-four patients with essential hypertension excluding common diseases causing changes in serum immunoglobulin levels were assayed for IgG, IgA, and IgM, and compared with 51 subjects in the normotensive group. The results showed that IgG was significantly increased (P <0.01), while IgG and IgA were significantly increased in patients with heart damage (P <0.01). Combined with the literature discusses the mechanism of immune function changes in hypertensive patients and its relationship with complications and treatment medication. Tip: Determination of Ig levels in patients with a certain clinical significance, IgA should be considered complicated by the possibility of excessive heart damage.