随着人口的老龄化 ,骨质疏松的发病率呈明显上升趋势 ,并已成为世界性疾病 ,由此引起的腰背痛、股骨颈及腰椎骨折等 ,给社会和老年人带来严重的负担和影响。为探讨骨质疏松模型的发病机理和寻找有效的防治措施 ,许多学者从制造骨质疏松模型入手致力于这方面的研究。Ｊｅｅ等曾? With the population aging, the incidence of osteoporosis is on the rise and has become a worldwide disease, resulting in low back pain, femoral neck and lumbar fractures, which bring a serious burden on the society and the elderly And influence. To explore the pathogenesis of osteoporosis model and to find effective prevention and treatment measures, many scholars from the manufacture of osteoporosis model to begin research in this area. Jee et al.