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布比卡因是一种长效局部麻醉药,本文比较应用几种不同麻醉药如普鲁卡因、利多卡因和布比卡因于内眼手术如白内障摘出、视网膜脱离复位术、角膜移植术等的麻醉效果。158例内眼手术根据所使用的麻醉药分为普鲁卡因、利多卡因、布比卡因和布比卡因加利多卡因混合4组。布比卡因组的诱导期(从注射至产生麻醉作用)和麻醉持续时间均比其它3组长(均为 P<0.001,有非常显著差异),虽然布比卡因的诱导期较长,但多数内眼手术于注射麻醉药后均需按摩眼球以降低眼压,故不影响手术的开始。利多卡因和布比卡因混合组的效果不比布比卡因组好,从本组研究的结果,证实布比卡因是一种长效麻醉药,无毒性,适用于眼科手术。
Bupivacaine is a long-acting local anesthetic, this article compares the use of several different anesthetics such as procaine, lidocaine and bupivacaine due to intraocular surgery such as cataract extraction, retinal detachment, corneal transplantation Such as anesthesia. 158 cases of intraocular surgery were divided into 4 groups of procaine, lidocaine, bupivacaine and bupivacaine plus lidocaine according to the anesthetic used. The induction period (from injection to anesthesia) and duration of anesthesia in the bupivacaine group were longer than those in the other three groups (all P <0.001, with very significant differences). Although the induction period of bupivacaine was longer, However, the majority of intraocular surgery after injection of anesthetics need to massage the eyeball to reduce intraocular pressure, it does not affect the beginning of surgery. The effect of the combination of lidocaine and bupivacaine was no better than that of the bupivacaine group. From the results of this study, bupivacaine is a long-acting anesthetic that is non-toxic and suitable for ophthalmic surgery.