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目的探讨血清降钙素原(PCT)、白细胞介素-6(IL-6)和C肽水平联合检测用于诊断急性胰腺炎的临床价值。方法选取150例急性胰腺炎疑似患者作为研究对象,发病24h内分别检测其血清PCT、IL-6及C肽水平,比较单独检测三指标及联合检测三指标对于急性胰腺炎的诊断价值。结果联合检测血清PCT、IL-6及C肽水平的真阳性、真阴性和准确度均明显高于单独检测以上三指标,差异均有统计学意义(P<0.05)。结论血清PCT、IL-6及C肽水平均可作为急性胰腺炎的临床诊断指标,联合检测三者能提高检测的灵敏度、特异度和准确度,能提高疾病的诊断价值,值得推广应用。
Objective To investigate the clinical value of combined detection of serum procalcitonin (PCT), interleukin-6 (IL-6) and C-peptide in the diagnosis of acute pancreatitis. Methods A total of 150 patients with acute pancreatitis were selected as the research objects. The levels of serum PCT, IL-6 and C-peptide were detected respectively within 24 hours after onset. The diagnostic value of three indexes and three indexes for acute pancreatitis were compared. Results The true positive, true negative and accuracy of the combined detection of serum PCT, IL-6 and C peptide levels were significantly higher than those of the above three indicators alone, the differences were statistically significant (P <0.05). Conclusions Serum PCT, IL-6 and C-peptide levels can be used as clinical diagnostic indicators of acute pancreatitis. The combination of three detection methods can improve the sensitivity, specificity and accuracy of detection, which can improve the diagnostic value of the disease and should be widely applied.