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目的:明确A组β溶血性链球菌感染是否会增加儿童发生自身免疫性神经精神异常综合征(PANDAS)的危险性。设计:前瞻性队列研究。方法:研究对象为2001年10月至2002年6月因咽喉痛而就诊于纽约罗彻斯特大型儿科实习基地或在儿科门诊接受健康查体
OBJECTIVE: To determine whether group A hemolytic streptococcal infection increases the risk of developing autoimmune neuropsychiatric syndrome (PANDAS) in children. Design: Prospective cohort study. Methods: The subjects were hospitalized at Rochester, NY, for pediatric sore throat and pediatric outpatient clinics from October 2001 to June 2002