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目地探讨磷酸肌酸钠治疗小儿轮状病毒肠炎合并心肌损害的疗效。方法轮状病毒肠炎合并心肌损害患儿64例,随机分为治疗组与对照组各32例,二组患儿均给予补液等对症治疗,在此基础上治疗组加用磷酸肌酸钠(CP)治疗,对照组加用1,6-二磷酸果糖(FDP)治疗。结果二组患儿治疗后心肌酶水平均显著下降(P<0.01),治疗组降低更明显,与对照组比较差异有统计学意义(P<0.05)。治疗组与对照组有效率分别为96.9%和75.0%,二组比较差异有统计学意义(P<0.05)。结论磷酸肌酸钠治疗小儿轮状病毒肠炎合并心肌损害具有良好疗效,效果优于1,6-二磷酸果糖。
Objective To investigate the efficacy of sodium creatine phosphate in treating pediatric rotavirus enteritis complicated with myocardial damage. Methods Sixty-four children with rotavirus enteritis and myocardial damage were randomly divided into treatment group (n = 32) and control group (n = 32). Patients in both groups were given symptomatic treatment such as rehydration. On the basis of this, ) Treatment, the control group plus fructose-1,6-diphosphate (FDP) treatment. Results The levels of myocardial enzymes in both groups were significantly decreased (P <0.01), and the treatment group decreased more obviously compared with the control group (P <0.05). The effective rates of the treatment group and the control group were 96.9% and 75.0%, respectively, with significant difference between the two groups (P <0.05). Conclusion Sodium creatine phosphate is effective in treating children with rotavirus enteritis complicated with myocardial damage, and its effect is better than fructose-1,6-diphosphate.