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目的研究七氟醚联合小剂量氯胺酮麻醉在小儿眼科手术中的效果。方法 50例年龄1～3岁择期行白内障手术的患儿,随机分为两组,七氟醚复合小剂量氯胺酮组(Ⅰ组)和氯胺酮组(Ⅱ组),观察两组诱导和苏醒时间,诱导时是否合作,喉痉挛、呕吐、术中体动和苏醒期躁动发生率。结果与Ⅱ组相比,Ⅰ组能较好接受诱导,诱导、苏醒时间短,术中体动及苏醒期躁动发生率低(P<0.05);两组呕吐和术中知晓发生率差异无统计学意义。结论七氟醚联合小剂量氯胺酮麻醉具有麻醉诱导、苏醒快,不良反应少,能较好地应用于小儿眼科手术。
Objective To study the effect of sevoflurane combined with low-dose ketamine anesthesia in pediatric ophthalmic surgery. Methods Fifty children aged 1-3 years undergoing elective cataract surgery were randomly divided into two groups: sevoflurane combined with low dose ketamine (group Ⅰ) and ketamine group (group Ⅱ). The induction and recovery time, Induction of cooperation, laryngospasm, vomiting, intraoperative and motor recovery during the onset of agitation. Results Compared with group Ⅱ, group Ⅰ received better induction, induction, shorter awakening time and less agitation during recovery and recovery (P <0.05). There was no statistical difference in the incidence of vomiting and intraoperative awareness Significance of learning. Conclusion Sevoflurane combined with low-dose ketamine anesthesia induction of fast recovery, fewer adverse reactions, can be better applied to pediatric ophthalmic surgery.