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目的:评价我院心血管介入诊疗手术预防用抗菌药物情况。方法:将我院2011年1-6月(第1阶段)173例心血管介入诊疗手术患者病历设为对照组,2011年7-12月(第2阶段)273例和2012年1-6月(第3阶段)378例手术患者病历设为持续干预组,对3个阶段预防用抗菌药物情况进行回顾性统计、分析。结果:通过采取多种持续、有效的干预措施,3个阶段的手术患者预防用药比例从第1阶段的83.82%下降至第2、3阶段的35.16%、15.87%,未用药比例从第1阶段的4.05%上升至第2、3阶段的61.17%、80.42%。从心血管介入诊疗手术是否有预防用药指征、药物品种选择、首次用药时机、用法用量、用药疗程等方面评价用药合理性,抗菌药物应用的合理比例从第1阶段的41.62%上升到第2、3阶段74.73%、91.53%。结论:重视和加强医院临床抗菌药物的应用管理,采取积极、有效的持续干预措施,有助于提高临床合理用药水平,从而确保患者用药安全、有效。
OBJECTIVE: To evaluate the situation of antimicrobial agents used in the prevention and treatment of cardiovascular intervention in our hospital. Methods: The medical records of 173 cardiovascular patients undergoing surgery in our hospital from January to June in 2011 (stage 1) were set as the control group, 273 cases in July-December 2011 (phase 2) and January-June 2012 (Stage 3) The medical records of 378 surgical patients were selected as the continuous intervention group. Retrospective statistics and analysis were conducted on the three stages of prophylactic antimicrobials. Results: By taking a number of continuous and effective interventions, the prophylactic prophylaxis of surgical patients in three stages decreased from 83.82% in stage 1 to 35.16% and 15.87% in stage 2 and stage 3, while the proportion of non-medication decreased from stage 1 4.05% to 61.17% and 80.42% in stages 2 and 3, respectively. From the cardiovascular interventional diagnosis and treatment of surgical prophylaxis indications, the choice of drug species, the first time of medication, usage dosage, medication and other aspects of evaluation of drug use rationality, a reasonable proportion of antimicrobial applications from the first phase of 41.62% to 2 , 74.73% in stage 3, and 91.53% in stage 3. Conclusion: Paying attention to and strengthening the management of clinical antibacterials in hospitals and taking active and effective continuous interventions will help to improve the rational clinical use of drugs and ensure the safety and effectiveness of the medication.