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报告２例ｉ（１２ｐ）阴性睾丸生殖细胞肿瘤核型分析结果，其中，４６ＸＹ，ｔ（３；４）作为睾丸生殖细胞肿瘤核型属首例报告。细胞遗传学研究提示，３号染色体短臂缺失（３ｐ－）可能与睾丸生殖细胞肿瘤的发生有关。１２号染色体非随机性变化进一步证实了其在该肿瘤产生中的作用，１２ｐ上基因放大与睾丸生殖细胞肿瘤密切相关。
Two cases of i (12p) negative testicular germ cell tumor karyotype analysis were reported, of which 46XY, t (3; 4) was the first report of testicular germ cell tumor karyotype. Cytogenetics studies suggest that chromosome 3 short arm deletion (3p-) may be related to the occurrence of testicular germ cell tumors. Non-random changes in chromosome 12 further confirmed its role in the tumorigenesis, gene amplification on 12p and testicular germ cell tumors are closely related.