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目的了解急性脑血栓患者用参芎葡萄糖注射液与奥扎格雷相联合治疗的临床应用价值。方法纳入对象来自本院2015年-2016年期间收治确诊急性脑血栓患者相关临床资料,选取60例后用随机数字表方式将其每组30例分为对照组(静脉滴注给药方式应用奥扎格雷)与观察组(联合参芎葡萄糖注射液治疗)。疗程后比较两种治疗方案临床疗效与安全性。结果分别于患者治疗后7天、30天、60天等不同时间段对神经功能缺损评分检测,提示观察组患者各阶段检测所得分数相对于对照组有显著优越性,统计学表示组间差异有意义(P<0.05);疗效评估后观察组、对照组无效患者例数分别为1例、9例,统计学处理组间总有效率差异有意义(P<0.05);所有患者治疗及随访期间均无发生严重不良反应。结论急性脑血栓患者接受参芎葡萄糖注射液联合奥扎格雷方案治疗对病情和患者生活质量改善效果相对更为突出,同时安全性高,患者接受程度高,值得临床推广。
Objective To investigate the clinical value of combined treatment of Shenxiong glucose injection and ozagrel in patients with acute cerebral thrombosis. Methods The clinical data of patients with acute cerebral thrombosis admitted to our hospital from 2015 to 2016 were enrolled in this study. Sixty patients were randomly divided into control group (30 cases in each group) by random number table Zagre) and observation group (combined Shengeng glucose injection treatment). After treatment, the clinical efficacy and safety of the two treatment plans were compared. Results The neurological deficit scores were detected at different time points of 7 days, 30 days and 60 days after treatment, which indicated that the score of each stage of the observation group was significantly superior to that of the control group. Statistical analysis showed that there were (P0.05) .After the curative effect was evaluated, the number of invalid patients in the observation group and the control group were 1 case and 9 cases, respectively. The total effective rate of the statistical treatment group had significant difference (P <0.05). All the patients were treated and followed up No serious adverse reactions occurred. Conclusion Acute cerebral thrombosis patients receiving Shenxiong glucose injection combined with ozagrel treatment on the condition and quality of life of patients is more prominent, while high safety, patients with high acceptance, it is worth clinical promotion.