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比较9例女性系统性红斑狼疮(SLE)患者并发冠心病(CAD)和年龄匹配的49例非SLE 早发 CAD 患者的传统危险因素。SLE 患者在发生首次心脏事件之前的 CAD 危险因素少于相同年龄段的非 SLE 早发 CAD 患者的危险因素[分别为(1.4±0.7)个/人和(2.2±1.2)个/人,P<0.05]。表明,SLE 患者早发 CAD 用传统危险因素不能完全解释,存在有其他疾病相关因素引起、促进 CAD 的进程。
Forty-nine patients with systemic lupus erythematosus (SLE) complicated with coronary heart disease (CAD) and age-matched traditional risk factors for 49 non-SLE patients with early-onset CAD were compared. The risk factors for CAD in SLE patients before onset of first heart event were less than those in non-SLE early onset CAD patients of the same age group (1.4 ± 0.7 vs 2.2 ± 1.2, respectively, P < 0.05]. It shows that the traditional risk factors of early-onset CAD in SLE patients can not be fully explained, there are other disease-related factors, and promote the process of CAD.