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目的比较子宫动脉栓塞(uterine artery embolization,UAE)与腹腔镜子宫肌瘤剔除术(laparoscopic myomecto-my,LM)治疗子宫肌瘤的费用-效果关系。方法2003年1月-2005年12月在广东药学院附属第一医院等采用微创治疗的157例子宫肌瘤患者,其中LM68例(腹腔镜组),UAE89例(介入组),比较两组患者的费用、疗效、平均住院日,计算两组的费用-效果比,并对术后远期效果及复发情况进行随访。结果157例子宫肌瘤患者实施微创治疗全部获得成功,两组疗效对比差异无统计学意义(P>0.05)。介入组与腹腔镜组例均费用分别为(6091±1682)元和(8216±1953)元,平均住院日分别为(4.1±1.2)d和(6.8±1.3)d,费用-效果比分别为60.9和82.2,经统计学检验差异有统计学意义(P<0.05或0.01)。随访至术后3年以上,两组长期效果及复发率差异无统计学意义(P>0.05)。结论相对于LM,UAE是一种费用-效果比更优的治疗方法。
Objective To compare the cost-effectiveness of uterine artery embolization (UAE) with laparoscopic myomecto-my (LM) in the treatment of uterine fibroids. Methods From January 2003 to December 2005, 157 cases of uterine leiomyoma treated by minimally invasive surgery, including the First Affiliated Hospital of Guangdong Polytechnic University, including 68 cases of laparoscopic group and 89 cases of UAE group, were compared between the two groups Patient’s cost, curative effect, average length of stay, calculate the cost-benefit ratio of both groups, and follow-up of postoperative long-term effects and recurrence. Results 157 patients with uterine fibroids minimally invasive treatment of all successful, no significant difference between the two groups (P> 0.05). The cost of interventional group and laparoscopic group were (6091 ± 1682) yuan and (8216 ± 1953) yuan respectively, the average hospitalization days were (4.1 ± 1.2) days and (6.8 ± 1.3) days, respectively. The cost- 60.9 and 82.2, statistically significant difference was statistically significant (P <0.05 or 0.01). Follow-up to more than 3 years after operation showed no significant difference in long-term efficacy and recurrence between the two groups (P> 0.05). Conclusion UAE is a more cost-effective treatment than LM.