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胃癌是我国主要的恶性肿瘤之一,其死亡率居恶性肿瘤的首位。近30年来,胃癌防治工作有了很大的进展:对病因有了进一步的认识;诊断有了很大的进步;治疗效果在不断提高。 对病因的进一步认识 胃癌的病因虽还未完全明了,但通过实验室研究和流行病学的调查,认为N-亚硝基化合物长期摄入,引起胃炎,逐渐发展为肠化生、不典型增生,最后导致胃癌。杂色曲霉素是胃癌的病因已在动物实验中得到证实。此外,A血型、遗传因素与胃癌的发生有密切关系。萎缩性胃炎、胃溃疡、胃腺瘤性息肉等癌前病变者容易发生胃癌。虽然胃癌的病
Gastric cancer is one of the major malignancies in China, and its mortality ranks first in malignant tumors. In the past 30 years, great progress has been made in the prevention and control of gastric cancer: there is a further understanding of the cause of the disease; diagnosis has made great progress; and the therapeutic effect is continuously improving. Further understanding of the cause of the disease Although the cause of gastric cancer is not yet fully understood, laboratory studies and epidemiological investigations suggest that long-term ingestion of N-nitroso compounds leads to gastritis and gradually develops intestinal metaplasia and atypical hyperplasia. Eventually lead to stomach cancer. Ochratoxin is the cause of gastric cancer has been confirmed in animal experiments. In addition, A blood group, genetic factors and the occurrence of gastric cancer are closely related. Atrophic gastritis, gastric ulcer, gastric adenomatous polyps and other precancerous lesions are prone to gastric cancer. Although gastric cancer