问:婴儿可否用肾上腺皮质激素,如何用? 答:外源性肾上腺皮质激素对内分泌系统的“稳定”机制常造成紊乱,从而诱发种种垂体肾上腺皮质系统的机能异常。这种情况对生后不久的婴儿,更为严重。因此,对婴儿使用激素要特别慎重,亦即要严格指征。婴儿的适应症有支气管哮喘、全身性湿疹、体质性腹泻,以及重症感染、休克等。制剂,最好用泼尼松龙(Prednisolone),勿用地塞米松(Dexamethasone),因后者有较强的抑制垂体的作用。剂量以泼尼松龙5—10毫克/日为度,不宜长期服用。待主要症状有了好转,即当停药,即使症状不见好转,亦应以无效论而停药。另外,为避免药剂的苦味,可给以矫味剂。对必需长期用药者,如红斑狼疮、风湿热、肾病等,要十分警惕副作用,如肥胖、痤疮、多毛、骨质疏松、身长发 Q: How to use adrenal cortex hormones in infants? A: Exogenous adrenal cortical hormones often cause disorders to the “stable” mechanism of the endocrine system, thereby inducing dysfunction of various pituitary adrenal cortical systems. This situation is even worse for infants born soon after birth. Therefore, the use of hormones in infants should be particularly cautious, that is, to be strictly indicated. Infant indications bronchial asthma, systemic eczema, physical diarrhea, and severe infection, shock and so on. Preparation, the best prednisolone (Prednisolone), do not use dexamethasone (Dexamethasone), because the latter has a stronger pituitary inhibitory effect. The dose of prednisolone 5-10 mg / day for the degree, not long-term use. When the main symptoms have improved, that is, when the withdrawal, even if the symptoms did not improve, should also be invalid theory and withdrawal. In addition, in order to avoid the bitterness of the agent, it can be given a flavoring agent. Long-term use of those who need, such as lupus, rheumatic fever, kidney disease, etc., be very wary of side effects such as obesity, acne, hirsutism, osteoporosis, long hair