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目的分析重度支气管哮喘合并真菌感染的治疗方法及临床疗效。方法回顾性分析20例重度支气管哮喘合并真菌感染患者的临床资料。结果全部患者的痰真菌涂片培养均为阳性,真菌菌株对氟康唑均存在敏感,氟康唑治疗后,临床体征、症状好转或者消失的患者占90%(18/20),2例患者因抢救无效而死亡。结论临床中常规治疗重度支气管哮喘合并真菌感染患者并不能取得比较理想的效果,临床中应对患者进行真菌培养和痰涂片检查,结合检查结果实施个性化的治疗,可提高临床治疗效果。
Objective To analyze the treatment and clinical efficacy of severe bronchial asthma complicated with fungal infection. Methods The clinical data of 20 patients with severe bronchial asthma complicated with fungal infection were retrospectively analyzed. Results All patients were positive sputum fungal smears, fungal strains were susceptible to fluconazole, fluconazole treatment, clinical signs, symptoms improved or disappeared accounted for 90% (18/20), 2 patients Death due to invalid rescue. Conclusion The clinical treatment of patients with severe bronchial asthma complicated with fungal infection can not achieve the desired effect. Patients should be treated with fungal culture and sputum smear in clinical practice. Combined with the results of the examination, personalized treatment can improve the clinical therapeutic effect.