论文部分内容阅读
Ekert和Jose初步报告结果提示,在急性淋巴细胞型白血病(ALL)中,以结核菌苗(BCG)联合化疗比单独化疗缓解期延长。Mathe′等进一步提供资料支持这种结论,并期望把存活曲线提高到治愈。另外,他们提出免疫治疗的效果是有希望的。相反,Heyn等发现BCG并不延长药物诱导缓解。本文作者报告10例ALL病人使用免疫疗法的5年随访。 10例ALL病人中6例成人和4例儿童,用长春新硷、强的松和L-天门冬酰胺酶诱导完全缓解。所有病人接受颅脑照射和鞘内注射氨甲喋呤预防脑膜白
Ekert and Jose preliminary report results suggest that in acute lymphoblastic leukemia (ALL), tuberculosis vaccine (BCG) combined chemotherapy than the chemotherapy alone to extend the remission. Mathe and others provide further support for this conclusion and look forward to raising the survival curve to cure. In addition, they proposed the effect of immunotherapy is promising. In contrast, Heyn et al found that BCG does not prolong drug-induced remission. The authors report a 5-year follow-up of 10 ALL patients using immunotherapy. 6 of 10 adults and 4 children with ALL were induced complete remission with vincristine, prednisone and L-asparaginase. All patients received cranial irradiation and intrathecal methotrexate to prevent meningeal white