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目的评价雾化吸入3%高渗盐水溶液联合复方异丙托溴铵治疗幼儿毛细支气管炎疗效。方法将80例毛细支气管炎患儿在常规抗感染、止咳、化痰、平喘治疗下,随机分成治疗组和对照组。治疗组40例,雾化吸入3%高渗盐水1.5mL+复方异丙托溴铵1.25 mL;对照组40例,雾化吸入生理盐水1.5 mL+复方异丙托溴铵1.25 mL,2组均每天2次,疗程均为7 d~10 d,比较2组咳嗽、喘息、肺部湿啰音消失时间、住院时间、不良反应及住院费用。结果 2组患儿均痊愈出院,治疗组在其咳嗽、喘息、肺部湿啰音消失时间、住院时间及住院费用等方面均优与对照组(P<0.05)。结论 3%高渗盐水联合复方异丙托溴铵高频雾化吸入治疗毛细支气管炎有效,并能减少住院时间,降低治疗费用。
Objective To evaluate the efficacy of nebulized inhalation of 3% hypertonic saline solution combined with ipratropium bromide in the treatment of infantile bronchiolitis. Methods Eighty children with bronchiolitis were randomly divided into treatment group and control group under conventional anti-infection, cough-relieving, phlegm-resolving and antiasthmatic treatment. In the treatment group, 40 cases were treated with atomization inhalation of 3% hypertonic saline 1.5 mL + compound ipratropium bromide 1.25 mL; control group 40 patients, inhaled saline 1.5 mL + compound ipratropium bromide 1.25 mL, both groups 2 Times, the course of treatment was 7d ~ 10d, compared two groups of cough, wheezing, lung wet rales disappear time, hospital stay, adverse reactions and hospitalization costs. Results The two groups were cured and discharged. The treatment group was superior to the control group in cough, wheezing, disappearance of pulmonary wet rales, hospital stay and hospitalization expenses (P <0.05). Conclusion 3% hypertonic saline combined with compound ipratropium bromide high-frequency atomization inhalation treatment of bronchiolitis effective and can reduce hospitalization time and reduce the cost of treatment.