论文部分内容阅读
目的探讨康复新液联合美沙拉嗪治疗溃疡性结肠炎(UC)的临床疗效。方法 64例轻中度UC患者,随机分为对照组和治疗组,各32例。两组均给予益生菌辅助治疗,对照组在此基础上采用美沙拉嗪治疗,治疗组采用美沙拉嗪联合康复新液保留灌肠治疗。治疗8周后观察对比临床疗效。结果治疗组完全缓解20例(62.50%),有效10例(31.25%),无效2例(6.25%),总有效率为93.75%;对照组完全缓解13例(40.63%),有效11例(34.38)%,无效8例(25.00%),总有效率为75.00%;两组患者临床症状总有效率比较差异有统计学意义(P<0.05)。治疗组完全缓解20例(62.50%),有效11例(34.38%),无效1例(3.13%),总有效率为96.88%;对照组完全缓解15例(46.88%),有效11例(34.38%),无效6例(18.75%),总有效率为81.25%;两组患者内镜下检查总有效率比较差异有统计学意义(P<0.05)。结论康复新液灌肠联合美沙拉嗪治疗UC,其疗效显著、确切而且安全,值得临床推广。
Objective To investigate the clinical effects of Kangfuxin Solution combined with Mesalazine in the treatment of ulcerative colitis (UC). Methods 64 patients with mild to moderate UC were randomly divided into control group and treatment group, 32 cases in each. Both groups were given probiotics adjuvant therapy, the control group on this basis with mesalazine treatment, the treatment group with mesalamine combined with rehabilitation of new fluid retention enema. After 8 weeks of treatment, the clinical efficacy was observed. Results The treatment group completely relieved 20 cases (62.50%), effective 10 cases (31.25%), ineffective 2 cases (6.25%), the total effective rate was 93.75%; the control group completely relieved 13 cases (40.63%), effective 11 cases 34.38)%, 8 cases (25.00%) were ineffective and the total effective rate was 75.00%. There was significant difference in the total effective rate of clinical symptoms between the two groups (P <0.05). In the treatment group, 20 cases (62.50%) were relieved completely, 11 cases (34.38%) were effective, 1 case (3.13%) ineffective, and the total effective rate was 96.88% %), 6 cases (18.75%) were ineffective and the total effective rate was 81.25%. There was significant difference between the two groups in the total effective rate of endoscopy (P <0.05). Conclusion Rehabilitation liquid enema combined with Mesalazine for the treatment of UC, the effect was significant, accurate and safe, worthy of clinical promotion.