青霉素G在基层医院仍较常用,其严重的不良反应为过敏性休克,发生率约占用药人数的0.015～0.04％,已引起医务工作者的高度重视。但该药引起的其他过敏反应发生率亦很高,约占用药人数的0.7～10％,药物热就是一种常见的不良反应。我院近3年来遇到青霉素G所致的药物热20例,报告如下。一、临床资料 1.一般资料 20例中男13例,女7例。年龄6～58岁。6例有变态反应性疾病(支气管哮喘、荨麻疹等)史,7例既往用过青霉素G。原发病(用青霉素G的原因)中肺炎7例,急性支气管炎4例,急性扁桃体炎5例,中耳炎1例,外科手术后预防感染 Penicillin G is still more commonly used in primary hospitals, and its serious adverse reaction is anaphylactic shock, the incidence of which accounts for 0.015 ~ 0.04% of the number of people who have taken medication. This has drawn great attention from medical workers. However, the incidence of other allergic reactions caused by the drug is also very high, accounting for about 0.7 to 10% of drug users, drug fever is a common adverse reaction. Nearly three years in our hospital encountered penicillin G caused by drug fever in 20 cases, the report is as follows. First, the clinical data 1. General Information 20 cases of male 13 cases, female 7 cases. Age 6 to 58 years old. Six patients had a history of allergic diseases (bronchial asthma, urticaria, etc.), and seven had previously used penicillin-G. Primary disease (with penicillin G reasons) pneumonia in 7 cases, 4 cases of acute bronchitis, acute tonsillitis in 5 cases, otitis media in 1 case, prevention of infection after surgery