根据《全国疟疾防治研究工作五年规划》提出的任务,中国医科院寄研所首先在实验室研制了砱酸咯萘啶,后由杭州第一制药厂进行了中间生产试验,于一九七九年六月完成了中试通过了鉴定,会议以为中试产品与小试产品一致、疗效显著, According to the task set out in the “National 5-year Malaria Prevention and Control Research Plan,” the Chinese Academy of Medical Sciences initiated the development of pyronyl citrate in the laboratory. After that, an intermediate production trial was conducted at Hangzhou No. 1 Pharmaceutical Factory in 1977. In mid-June, we completed the pilot test and passed the appraisal. The meeting concluded that the pilot product is consistent with the small test product and the curative effect is significant.