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目的探讨综合护理干预对胃癌化疗患者化疗依从性与营养状态的影响。方法选取2014年2月至2016年2月间大连医科大学附属大连市中心医院收治的104例胃癌患者作为研究对象,采用随机数表法分为研究组和对照组,每组52例。研究组患者在常规护理基础上采用综合护理,对照组患者采用常规护理。观察并比较两组患者的化疗依从性、治疗后体质量降低百分率和治疗前后的营养指数(PNI)。结果研究组患者化疗依从率为98.1%,高于对照组患者80.8%,差异有统计学意义(P<0.05)。两组患者治疗前PNI比较,差异无统计学意义(P>0.05)。化疗后,研究组患者体质量降低的百分率为(11.2±1.5)%,低于对照组患者的(6.7±0.8)%,研究组患者的PNI为(46.5±6.2),高于对照组患者的(42.8±5.5),差异均有统计学意义(均P<0.05)。结论综合护理干预措施能够提高胃癌化疗患者的化疗依从性,同时也可改善患者营养状况,适于临床推广与应用。
Objective To investigate the effect of comprehensive nursing intervention on chemotherapy compliance and nutritional status in gastric cancer patients undergoing chemotherapy. Methods A total of 104 patients with gastric cancer admitted to Dalian Central Hospital Affiliated to Dalian Medical University from February 2014 to February 2016 were selected as study subjects and divided into study group and control group with 52 cases in each group. Patients in the study group were treated with general nursing based on routine care while those in control group were treated with routine care. Observe and compare the two groups of patients with chemotherapy compliance, weight loss after treatment and nutritional index before and after treatment (PNI). Results The compliance rate of chemotherapy in the study group was 98.1%, which was higher than that in the control group (80.8%), the difference was statistically significant (P <0.05). There was no significant difference in PNI between the two groups before treatment (P> 0.05). After chemotherapy, the reduction in body mass was (11.2 ± 1.5)% in the study group compared with 6.7 ± 0.8% in the control group (46.5 ± 6.2) in the study group, which was significantly higher in the study group than in the control group (42.8 ± 5.5), the differences were statistically significant (all P <0.05). Conclusion The comprehensive nursing intervention can improve the chemotherapy compliance of patients with gastric cancer chemotherapy, meanwhile, it can also improve the nutritional status of patients and is suitable for clinical promotion and application.