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测定了１７例胰头癌伴梗阻性黄疸病人手术前后血清可溶性白细胞介素－２受体的变化。结果表明术前其水平较正常人明显升高，手术后１周即有下降，３周时明显下降但仍较正常人高，且其浓度与直接胆红素及碱性磷酸酶呈正相关。提示恶性肿瘤本身及梗阻性黄疸皆可引起可溶性白细胞介素－２受体升高，当通过各种方式减黄后，其水平逐渐降低，病人的免疫功能也得到某种程度的恢复。
The serum levels of soluble interleukin-2 receptor in 17 patients with pancreatic head cancer and obstructive jaundice were measured before and after surgery. The results showed that the preoperative levels were significantly higher than those in normal subjects, decreased one week after surgery, decreased significantly at three weeks but still higher than normal, and the concentration was positively correlated with direct bilirubin and alkaline phosphatase. It is suggested that the malignant tumor itself and obstructive jaundice can all cause soluble interleukin-2 receptor elevation. When the yellowing is reduced by various methods, its level gradually decreases, and the patient’s immune function also recovers to some extent.