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目的探讨采用复方甘草酸苷治疗慢性乙型肝炎的临床疗效。方法将慢性乙型肝炎患者60例,随机分为观察组和对照组各30例,观察组给予复方甘草酸苷治疗,对照组给予甘草酸二铵治疗,比较两组患者治疗后的肝功能指标以及不良反应。结果治疗4周后,观察组的总有效率为100%,对照组的总有效率为86.67%,观察组明显高于对照组,两组比较,差异有统计学意义(P<0.05)。两组患者在治疗过程中均未见明显不良反应。结论复方甘草酸苷治疗慢性乙型肝炎临床疗效确切,并且安全性高,不良反应小,值得临床推广应用。
Objective To investigate the clinical efficacy of compound glycyrrhizin in the treatment of chronic hepatitis B. Methods Sixty patients with chronic hepatitis B were randomly divided into observation group and control group, 30 cases in each group. The observation group was treated with compound glycyrrhizin. The control group was given glycyrrhizic acid diammonium treatment. The liver function indexes And adverse reactions. Results After 4 weeks of treatment, the total effective rate of the observation group was 100%, while the total effective rate of the control group was 86.67%. The observation group was significantly higher than the control group. There was significant difference between the two groups (P <0.05). Two groups of patients in the course of treatment showed no significant adverse reactions. Conclusion Compound glycyrrhizin is effective in treating chronic hepatitis B and has high safety and little adverse reactions. It is worthy of clinical application.