目的探讨机械通气治疗急重症颅脑损伤合并急性呼吸窘迫综合征(ARDS)的有效性和可行性。方法回顾性分析47例急重症颅脑损伤合并ARDS患者的治疗过程。结果本组患者均给予人工开放气道及呼吸机辅助呼吸,13例死亡,死亡率为27.66%。结论早期诊断并尽早呼吸机治疗可有效降低本病的死亡率。 Objective To investigate the effectiveness and feasibility of mechanical ventilation in the treatment of acute severe head injury combined with acute respiratory distress syndrome (ARDS). Methods Retrospective analysis of 47 cases of acute severe head injury patients with ARDS treatment. Results The patients were given artificial open airway and ventilator assisted breathing, 13 patients died, the mortality rate was 27.66%. Conclusion Early diagnosis and early ventilator treatment can effectively reduce the mortality of this disease.