六甲基磷酰胺(hexamethylphosphoramide.简称HMPA)是一种强有力的溶剂,它对实验动物的经口、吸入和经皮急性毒性,为低毒至中等毒性,并对皮肤有刺激性。但其慢性毒性则更为严重。HMPA又是一种有效的化学杀虫剂,对数种病虫有致畸作用,并干扰大鼠的生精作 Hexamethylphosphoramide (HMPA) is a potent solvent that has low toxicity to moderate toxicity and is irritating to the skin due to its oral, inhaled and acute dermal toxicity to experimental animals. But its chronic toxicity is even more serious. HMPA is another potent chemical insecticide that teratogenic to several species of pests and interferes with rat spermatogenesis