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人类T-细胞白血病-淋巴瘤病毒(HTLV)是一种从白血病和成熟T-细胞淋巴瘤成人患者中分离出来的C型逆病毒(retrevirus).这种病毒已经先后从美国和日本的成人患者中得到分离.本文描述了从世界不同地区分离到的9种新HTLV分离物,证明了每种分离物可感染索状血组织;而且HTLV不仅可从进行性和非进行性成人T-细胞白血病患者中分离出来,甚至也可以从具有临床表现“正常”个体的异常T-细胞中分离出来.这些新的HTLV阳性T-细胞株都是通过使用T-细胞生长因子(TCGF)从患者的外周血或骨髓
Human T-cell leukemia-lymphoma virus (HTLV) is a type C retrevirus isolated from adult patients with leukemia and mature T-cell lymphoma that has been isolated from adult patients in the United States and Japan .In this paper, we describe 9 new HTLV isolates isolated from different parts of the world and demonstrate that each isolate can infect cord-like blood cells; and that HTLV not only infects both progressive and non-progressive adult T-cell leukemia Isolated from patients and even isolated from abnormal T-cells with “normal” individuals with clinical manifestations.These new HTLV-positive T-cell lines are obtained from the patient’s periphery by using T-cell growth factor (TCGF) Blood or bone marrow