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本文用标准微量淋巴细胞毒试验及62种HLA抗血清对青岛地区56例脑血栓病人的HLA-A-B-Cω抗原进行了测定,并以72例健康人作对照。结果发现,脑血栓组HLA-A_(68),B_5,B_(16),Cω_(10)相对危险率高于对照组,经相对危险率x~2检验,只有HLA-B_5抗原(P<0.05)和HLA-B_(16)(P<0.05)有统计学意义。提示青岛地区脑血栓病人可能与HLA-B_5,B_(16)抗原相关联。但由于标本量少,经校正后P>0.05,所以对脑血栓与HLA抗原关联的研究有待进一步深入。
In this paper, we measured the HLA-A-B-Cω antigen in 56 cases of cerebral thrombosis patients in Qingdao by standard microlymphocytotoxicity test and 62 kinds of HLA antisera, and 72 healthy people as control. The results showed that the relative risk of HLA-A 68, B 5, B 16 and C 10 in the cerebral thrombosis group was higher than that in the control group. Only the HLA-B 5 antigen (P <0.05) ) And HLA-B_ (16) (P <0.05) were statistically significant. It is suggested that patients with cerebral thrombosis in Qingdao may be associated with HLA-B_5 and B_ (16) antigens. However, due to the small sample size, after correction of P> 0.05, so the study of cerebral thrombosis and HLA antigen needs further study.