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目的 探讨抗心磷脂抗体 (AcA)与病理性妊娠的关系 .方法 胎儿宫内发育迟缓 (IUGR) 144例为观察组A ,妊高征 (PIH) 98例为观察组B ,30例正常孕妇为对照组 .用酶联免疫吸附法 (ELISA)检测血清中的AcA .结果 观察组A的AcA阳性 32例 (2 2 .2 % ) ;观察组B阳性 12例 (12 .2 % ) ;对照组阳性 1例 (3 .3 % ) .观察组A、B分别与对照组抗体阳性率比较有明显差异 .结论 IUGR及PIH发病与体内AcA的存在有关 .
Objective To investigate the relationship between anticardiolipin antibody (AcA) and pathological pregnancy.Methods 144 cases of intrauterine growth retardation (IUGR) were observed in group A. 98 cases of PIH were observed in group B. 30 cases of normal pregnant women were Control group.The level of AcA in serum was detected by enzyme-linked immunosorbent assay (ELISA) .ResultsA AcA positive in group A was observed in 32 cases (22.2%), in group B in 12 cases (12.2%), in control group Positive in 1 case (3.3%) .The positive rate of antibody in group A and B was significantly different from that in control group.Conclusion The incidence of IUGR and PIH is related to the presence of AcA in vivo.