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应用电镜x射线显微分析仪电子探针x射线微量分析,测试人体肝细胞癌中不同部位微量元素含量。结果表明:肝癌细胞内Cu含量差异显著高于正常;Al和Zn则低于正常;癌旁肝细胞核内Cu含量差异显著高于癌中心细胞核及胞浆。提示:癌旁肝细胞内Cu的沉积,在肝细胞癌的癌变中可能起阻抗作用。
Electron microscopy x-ray microanalyzer was used to analyze the content of trace elements in human hepatocellular carcinoma. The results showed that the difference of Cu content in hepatocellular carcinoma cells was significantly higher than normal; Al and Zn were lower than normal; the content of Cu in the nucleus of adjacent hepatocellular carcinoma cells was significantly higher than that in the nucleus and cytoplasm of the cancer center. Tip: The deposition of Cu in liver cells adjacent to cancer may play an inhibitory role in the carcinogenesis of hepatocellular carcinoma.