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目的：探讨慢性肾功能衰竭有效的非透析治疗方法，以提高治愈率。方法：慢性肾功能衰竭患者１３４例，随机分为治疗组６８例和对照组６６例。对照组采用常规西药治疗；治疗组在西药治疗的基础上加用降氮汤灌肠治疗，其中２６例根据临床辨证分型给予口服中药治疗。２组均以２０日为１个疗程。结果：治疗组治疗后血尿素氮〔ＢＵＮ，（１７．４６±６．８７）ｍｍｏｌ／Ｌ〕和血肌酐〔ＳＣｒ，（６３８．００±２１０．２０）μｍｏｌ／Ｌ〕均显著低于对照组〔分别为（２０．８０±６．４０）ｍｍｏｌ／Ｌ和（８１０．００±２１２．２０）μｍｏｌ／Ｌ〕，Ｐ均＜０．０５；血浆总蛋白和白蛋白〔分别为（５９．２０±２．８０）ｇ／Ｌ和（３７．２０±２．１０）ｇ／Ｌ〕均显著高于对照组〔分别为（５３．４０±２．６０）ｇ／Ｌ和（３０．２０±２．１０）ｇ／Ｌ〕，Ｐ均＜０．０５。治疗组总有效率为８５．３０％，对照组为６５．２０％，２组疗效差异显著（Ｐ＜０．０５）。结论：中西医结合治疗慢性肾功能衰竭可降低血ＢＵＮ、ＳＣｒ，升高血浆总蛋白和白蛋白，改善肾功能，疗效优于单纯西医药治疗。
Objective: To explore the effective non-dialysis treatment of chronic renal failure in order to improve the cure rate. Methods: A total of 134 patients with chronic renal failure were randomly divided into treatment group (n = 68) and control group (n = 66). The control group was treated with conventional western medicine. The treatment group was treated with Jiangni Decoction on the basis of western medicine treatment, of which 26 cases were treated with oral traditional Chinese medicine according to clinical syndrome differentiation. 2 groups were on the 20th for a course of treatment. Results: After treatment, BUN (17.46 ± 6.87) mmol / L and SCr (638.00 ± 210.20 μmol / L) in the treatment group were significantly lower than those in the control group 〔(20.80 ± 6.40) mmol / L and (810.00 ± 212.20) μmol / L, P <0.05 respectively; total plasma protein and albumin 〔(59.20 ± 2.80) g / L and (37.20 ± 2.10) g / L] were significantly higher than those in the control group [53.40 ± 2.60 g / L and 30.20 ± 2 .10) g / L], P <0.05. The total effective rate was 85.30% in the treatment group and 65.20% in the control group, with significant difference between the two groups (P <0.05). Conclusion: Integrative Chinese and Western medicine treatment of chronic renal failure can reduce blood BUN, SCr, increase plasma total protein and albumin, improve renal function, the effect is superior to Western medicine alone.