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众所周知,生物因子是人和动物致癌的危险因素。乙型肝炎患者对黄曲霉素B_1诱发原发性肝癌具有促进作用,疱疹二型病毒感染可提高某些致癌物对细胞的恶性转化,肠道蠕虫感染与肝细胞增生和胆囊或胆管癌发生有关系,感染血吸虫的人胆囊癌发病率升高。为了阐明寄生虫感染对癌症发生的作用,作者研究了血吸虫感染与外源性化学诱变物代谢的关系。实验动物使用叙利亚金黄地鼠,以血吸虫尾蚴经皮感染受试动物,通过检验动
As we all know, biological factors are human and animal carcinogenesis risk factors. Hepatitis B patients have a promoting effect on aflatoxin B 1 -induced primary hepatocellular carcinoma. Herpes type 2 virus infection can improve the malignant transformation of some carcinogens to cells, intestinal worm infection and hepatocyte proliferation and gallbladder or cholangiocarcinoma Related, people infected with schistosomiasis gallbladder cancer incidence increased. In order to elucidate the role of parasite infection in cancer development, the authors studied the relationship between schistosome infection and the exogenous chemical mutagenesis. Experimental animals Syrian golden hamster, infected with cercariae schistosome cercaria percutaneous test animals, through the test