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作者等用细胞免疫试验对硝硫氰胺治疗慢性血吸虫病所致黄疸的发病机制进行了探讨。通过对广汉县33例硝硫氰胺所致黄疸并发肝功能损害的病人(均系1979～1980年内口服该药的慢性血吸虫病病人)、23例服硝硫氰胺无黄疸及肝功能损害的病人(均系1980年11月口服该药的慢性血吸虫病病人)和20例从未接触过该药的健康人(重庆献血员)的淋巴细胞转化试验、白细胞移动抑制试验及硝硫氰胺皮肤试验的对比观察,进一步探讨其发病机制中是否存在过敏因素。
The authors used cellular immunization tests to investigate the pathogenesis of the treatment of jaundice caused by chronic schistosomiasis with nitrofurazone. Thirty-three patients with jaundice-induced liver dysfunction caused by nitrofurazone in Guanghan county (all patients with chronic schistosomiasis who took the medicine from 1979 to 1980) and 23 patients without jaundice and jaundice without liver dysfunction Patients (both chronic schistosomiasis patients who took the drug in November 1980) and lymphoid transformation test of 20 healthy donors who had never been exposed to the drug (Chongqing blood donors), leukocyte migration inhibition test and nitritamide skin Test the contrast observation to further explore the pathogenesis of allergic factors.