小分子多肽与人类免疫缺陷病毒感染的关系

来源 :临床内科杂志 | 被引量 : 0次 | 上传用户：jinhait2009

【摘要】

：

目的探讨人类免疫缺陷病毒(HIV-1)感染者体内可能存在的保护性中和抗体.方法应用ELISA等方法检测正常对照人群、HIV-1感染无症状组、长期生存组和艾滋病患者体内小分子多肽抗

【作者】

：

徐小元

【机构】

：

北京大学第一医院感染科,河北省秦皇岛市第三医院,兰州医学院附属一院感染科,法国马赛U322.INSERM

【出处】

：

临床内科杂志

【发表日期】

：

2004年期

【关键词】

：

人类免疫缺陷病毒多肽抗体

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论文部分内容阅读

目的探讨人类免疫缺陷病毒(HIV-1)感染者体内可能存在的保护性中和抗体.方法应用ELISA等方法检测正常对照人群、HIV-1感染无症状组、长期生存组和艾滋病患者体内小分子多肽抗体(抗-R7V)分布状况.结果抗-R7V在无症状组和长期存活组中检出率较高,而在进展者和艾滋病患者中存在较低,并发现抗-R7V能中和HIV RNA.结论抗-R7V的存在与病情进展有密切关系,能够使HIV感染者长期处于无进展状态,延缓或者阻止感染者发展为艾滋病.

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