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本文回顾了温度升高对精子发生的影响,包括单纯加热、电磁能与超声波。从加热引起睾丸损伤的细胞学变化,可见到睾丸的不同细胞成份对热损伤有不同的敏感性,最初受损的为初级精母细胞,其次为精子。超声波与微波对睾丸的损伤还存在非热效应。加热还可能改变睾丸的内分泌功能。现有知识提示在人类中采用睾丸加热作为可逆的男性避孕方法有潜在可行性,但在应用前应解决下列问题:维持可靠不育状态的最底有效量,睾丸功能变化的可逆性,对性腺的致突变可能等。
This article reviews the effects of elevated temperature on spermatogenesis, including simple heating, electromagnetic energy and ultrasound. From the cytological changes that cause testicular damage caused by heating, it can be seen that the different cellular components of the testes have different sensitivities to thermal damage, initially being primary spermatocytes, followed by sperm. Ultrasonic and microwave damage to the testes also exist non-thermal effects. Heating may also change the endocrine function of the testis. Current knowledge suggests that the use of testicular heating in humans as a reversible male contraceptive method is potentially viable, but the following issues should be addressed prior to use: the most effective dose to maintain a viable infertility state, the reversibility of testicular function changes, Mutagenesis may be so.