苯和酚对外周血淋巴细胞微核率影响的观察

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动物实验和调查均证实苯可诱导微核产生,苯的遗传毒性与其代谢产物有一定关系也为许多实验所证实。酚为苯的代谢产物之一,关于酚作业工人遗传毒作用的调查国内尚无报道,为了探讨酚的致微核作用,研究苯中毒作用机理,我们对接苯和接酚工人进行了微核水平实验检查,同时对苯作业工人工龄及白细胞与微核率关 Animal experiments and investigations confirm that benzene can induce the production of micronuclei, and the genetic toxicity of benzene has some relationship with its metabolites, which is confirmed by many experiments. Phenol is one of the metabolites of benzene. There is still no report about the genetic toxicity of phenol workers in China. In order to investigate the micronuclei induced by phenol and the mechanism of benzene poisoning, we conducted micronucleus levels Experimental inspection, at the same time workers working age benzene and leucocytes and micronuclei rate
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