【摘 要】
：
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle,metabolic diseases,chronic inflammatory disease,and cancer de
【机 构】
：
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia
论文部分内容阅读
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle,metabolic diseases,chronic inflammatory disease,and cancer development.A better understanding of the mechanisms of TRIB pseudokinases could provide new insights for disease development and help promote TRIB proteins as novel therapeutic targets for drug discovery.At the 2nd Inteational Symposium on Tribbles and Diseases held on May 7-9,2018 in Beijing,China,a group of leading Tribbles scientists reported their findings and ongoing studies about the effects of the different TRIB proteins in the areas of immunity,metabolism,fundamental cell biology and cancer.Here,we summarize important and insightful overviews from 4 keynote lectures,13 plenary lectures and 8 short talks that took place during this meeting.These findings may offer new insights for the understanding of the roles of TRIB pseudokinases in the development of various diseases.
其他文献
Traditional Chinese herbs (TCH) are currently gaining attention in disease prevention and health care plans.However,their general bitter taste hinders their use
宁夏银川大河数控机床有限公司(原大河机床厂)是全国机床工具行业骨干企业之一。公司拥有先进的西德导轨磨床、瑞士坐标镗床、德国齿轮磨床、日本A M A D A公司的数控剪板机
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues,organs,cells and subcellular organs for drug release and abso
萍乡莲花落是萍乡坐唱中的一种。自古以来经过不断的演变和发展传唱至今并具有一定的教化功能。萍乡莲花落目前已经被列为国家非物质文化遗产,本文列举萍乡莲花落的经典名段
A great challenge in multi-targeting drug discovery is to identify drug-like lead compounds with therapeutic advantages over single target inhibitors and drug c
泰顺县地处浙南山区,境内年日均温16.1℃,无霜期222—287天,日照17592小时,太阳辐射总量为101.96千卡/厘米~2,3—6月富水期降雨量为908.6毫米,占全年的45.79%。全县耕地面积
Mitochondrial targeting is a promising approach for solving current issues in clinical application of chemotherapy and diagnosis of several disorders.Here,we di
经常收看电视,大家有个比较,觉得各地电视台举办的生活类节目,除中央电视台的《为您服务》节目之外,江苏电视台的《衣食住行》节目也很受观众欢迎。《衣食住行》节目有个最
温907系温州市农科所用温选青/IR29Ⅲ温选青//浙辐802/桂朝2号复交选育而成的。1991年参加本所联合试验,亩产446.7公斤,比二九丰增产11.8%。1992年
Temperature 907 Depart
国际新闻是中央电视台收视率最高的节目之一,深受全国亿万观众的喜爱,它开播7年来,已成为广大群众观察世界、开阔视野、获知信息的重要窗口。中央电视台的国际新闻素材主要