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目的:观察健脾抑瘤汤对晚期原发性肝癌患者生活质量的影响。方法:60例患者随机分成治疗组(30例)与对照组(30例),两组患者均采用相同的西药疗法,治疗组同时加用健脾抑瘤汤治疗,1个月1个疗程,2个疗程评价疗效。观察两组患者生活质量变化及生存率比较和中医证候疗效变化情况。结果:两组生活质量变化比较,治疗组与对照组总稳定率分别为73.3%、56.7%(P<0.05);两组生存率比较,两组患者3个月～1年的生存率比较差异有显著性(P<0.05,P<0.01)。两组中医证候疗效比较,治疗组与对照组总改善率分别为76.7%、46.7%(P<0.05)。结论:健脾抑瘤汤可提高晚期原发性肝癌患者的生活质量,延长生存期,无毒副作用。
Objective: To observe the effect of Jianpi Yiliu Decoction on the quality of life of patients with advanced primary liver cancer. Methods: Sixty patients were randomly divided into treatment group (30 cases) and control group (30 cases). Both groups were treated with the same western medicine. The treatment group was treated with Jianpi Yiliu Decoction at the same time, one course of treatment for one month, 2 courses evaluate the curative effect. The changes of the quality of life and the survival rates of the two groups were observed and the changes of TCM syndromes were observed. Results: Compared with the control group, the total stability of the treatment group and the control group were 73.3% and 56.7% respectively (P <0.05). The survival rates of the two groups were significantly different from 3 months to 1 year There was significant (P <0.05, P <0.01). The two groups of TCM syndromes, the treatment group and control group, the overall improvement rates were 76.7%, 46.7% (P <0.05). Conclusion: Jianpi Yiliu Decoction can improve the quality of life of patients with advanced primary liver cancer, prolong survival and have no toxic and side effects.